Abstract
Summary
Genetically obese mice initially gained less body weight when fed diets containing fructose in comparison to mice fed starch, sucrose, or glucose diets. Plasma glucose concentrations were significantly lowered by fructose diets in both obese and nonobese mice in comparison to starch and glucose but not sucrose diets. Fructose or sucrose feeding did not induce hypertriglyc-eridemia in obese or nonobese mice as has been shown in the rat. In fact, the fructose diet significantly lowered plasma triglycer-ide concentrations in nonobese mice.
The authors express their appreciation to Rosemary Carr and Olden Green for expert technical assistance provided for this study. This research was supported by USPHS Research Grants Nos. AM 00106 and AM 02911, a grant from the Finn-Cal Sweetener Company, San Francisco, and the Fund for Research and Teaching, Department of Nutrition, Harvard School of Public Health.
Get full access to this article
View all access options for this article.