Abstract
Summary
From 5 to 10% of the biological activity of a porcine relaxin concentrate is contained in a fraction with a molecular weight which is considerably higher (∼42,000 daltons) than that of relaxin itself. Exposure of this material to a low concentration of trypsin results in the appearance of native relaxin, as judged by an increase in biological activity and changes in its chromatographic and electrophoretic properties.
Presented at the 67th Annual Meeting of the American Society of Biological Chemists. San Francisco, California, June 6-10, 1976. From a thesis submitted by Li-An Yeh in partial fulfillment of the requirements for the M.S. degree. Supported in part by a research grant from Hynson, Westcott, and Dunning, Inc., Baltimore, Maryland.
Get full access to this article
View all access options for this article.