Abstract
Summary
Porcine corpus luteum tissue contains an inhibitor of binding of iodinated human chorionic gonadotropin to porcine granulosa cells. The inhibitor was present in the 1000, 30,000, and 105,000g supernatants of the corpus luteum but not in those of nonluteal ovarian tissue, granulosa cells, lung, or heart tissue. The inhibitor appeared only after storage in the freezer for from 1.5 to 11 weeks. Freezing heart, lung, or nonluteal tissue for a comparable time period did not lead to an increase in inhibitory activity.
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