Effect of Captopril on the Blood Pressure Response to Angiotensin I in Turkeys 1

Abstract

These studies were designed to determine the presence of an angiotensin-converting enzyme in turkeys. Captopril, a converting enzyme inhibitor, prevented the elevation of diastolic, systolic, and mean blood pressures which occurs characteristically in response to administration of angiotensin I. However, the responsiveness of blood pressure to administration of angiotensin II and norepinephrine was maintained. Thus, the results suggest the presence of an angiotensin-converting enzyme in turkeys.