Comparative Litter and Reproduction Characteristics of Mouse Populations for 82 Generations of X-Irradiated Male Progenitors 1

Abstract

Male mice have been exposed to 200 rad of X rays (acute whole-body exposures) for 82 consecutive generations. Comparative studies on the reproductive capacity of two sublines (H2^k and H2^f) from the X-ray exposed line with the control line with no exposure to ionizing radiation above background were done. Irradiated line H2^f mice were significantly affected by 82 generations of X-ray exposure. However, irradiated line H2^k mice were no different than control line mice.