Comparison of Mammary Glands of Normal and Ovariectomized Rhesus Monkeys. ∗

Four monkeys were ovariectomized for periods ranging from 7 days to 6 months before autopsy. The ovaries were sectioned and found complete. The mammary glands were carefully dissected at autopsy, fixed, stained, mounted, and compared with a group of 5 unspayed controls of the same average body weight. The gland-areas from the spayed animals were not determinably different from the gland-areas of the controls. One gland from a subject spayed 6 months before death contained almost no bud tissue. Although there was a wide variation in the amount of bud-tissue present, the ducts of these ovariectomized animals did not retrogress.