Further experimental and clinical observations on the transfusion of blood

The therapeutic results may be grouped into three classes: positive, negative and undetermined. Among the positive results is transfusion in acute hemorrhage which is apparently final. In pathologic hemorrhage it has proven positive in improving the patient's immediate condition, and in most instances wholly controlled the hemorrhage itself. In shock its value seems far greater than any other remedy hitherto employed by me. From the experimental standpoint it seems to be the most effective treatment of illuminating gas poisoning.

Among the negative results are transfusion in pernicious anemia, leukemia, carcinoma, strychnin poisoning and diphtheria toxemia.

Among the undetermined results may be mentioned chronic suppuration with its attendant debility and anemia, tuberculosis and the acute self-limited diseases.

Of the twenty one clinical cases, all were technically successful.

In every instance the donee experienced a heightened vitality, and in the absence of serious organic disease the patient became buoyant, even jocose. Some had chills during transfusion or soon after, and a majority showed some febrile reaction later.