Abstract
About two years ago in a communication before this society we indicated the most favorable conditions for the decomposition of uric acid by tissues.
Several papers on the same subject have recently been published in which it was demonstrated that uric acid may suffer decomposition through the action of tissue extracts in the presence of dilute sodium bicarbonate.
This confirms the results in our previous paper. In our recent work uric acid was subjected to the action of splenic pulp in the presence of 2 per cent, ammonium hydroxide and 2 per cent, acetic acid.
Under both conditions uric acid was decomposed to the amount of 50 per cent, of that present. Allantoin was one of the decomposition products. In the first communication mention was made of the fact that basic substances were formed in the process of dissolution.
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