Detoxication of Borneo1 by Glucuronic Acid in Humans

Summary

(1) The ingestion of 2 g of borneol by 8 normal subjects resulted in the excretion, within 24 hours, of an average of 94% in the form of its glucuronide, the range being from 79 to 104%. (2) The ingestion of 1 g of borneol by 26 normal subjects resulted in the excretion, within 24 hours, of an average of 81%, the range being from 60 to 100%. (3) Fifty percent of the subjects, on ingesting 1 g of borneol, gave a maximum excretion in 3 to 6 hours, while 35% gave it in 6 to 9 hours. (4) The detoxication of 1 g of borneol by the 26 subjects was almost complete in 15 hours, the average value at that time being about 96% of that obtained in 24 hours.