Effect of Oral and Parenteral Administration of Vitamin E on Creatinuria and Symptoms of Dystrophic Rabbits. ∗

Conclusions

The oral administration of 20 mg of α-tocopherol to dystrophic rabbits produces a rapid fall in the urinary creatine. Following the parenteral administration of the same dose, the creatine remains at a high level, and the creatinine decreases. The injection of massive doses of α-tocopherol cures dystrophy in some cases, while in others it extends life and promotes growth for several months without curing the symptoms of the disease.