Abstract
Conclusions
Coupled extrasystoles appear in dogs following epicardial or sub-epicardial application of hypertonic solutions of sodium or barium chloride on circumscribed areas. Warming of the injected area increases the number and the rate of the extrasystoles or causes them to appear even if they were not present after the injection. Cooling the area of injection slows the rate of formation of extrasystoles or abolishes them completely.
These results can be explained satisfactorily by assuming a heterogenetic stimulus formation in the treated area.
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