Abstract
Summary
The administration of testosterone to rats, provided the initial injection is given during late estrus, leads to an enhanced and prolonged function of the corpora lutea, so that deciduomata can be produced by trauma tization of the uterus. The minimal total dosage necessary to produce this effect is between 2.5 and 5.0 mg, given over a period of 10 days. If it is increased to 20 mg there is, in addition, a marked hypertrophy of the corpora lutea cells, similar to that of normal pregnancy.
A similar administration of prolactin in total dosages of from 600 to 2400 I.U. produces active corpora lutea, as shown by deciduoma formation, but there occurs no hypertrophy of the luteal cells.
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