Muscle Glycogen as Influenced by Castration,Adrenalectomy,and Treatment with Testosterone and Desoxycorticosterone Acetate

Conclusions

Schumann's results are not confirmed. From the data in Table I, it appears that: 1. Castration did not significantly alter muscle glycogen concentration. 2. Neither testosterone nor desoxycorticosterone, in the dosages used, affected the concentration of glycogen in the gastrocnemius muscle of the intact or the castrated male rat. 3. Neither testosterone nor desoxycorticosterone restored to normal the low muscle glycogen levels found in adrenal insufficiency. This finding, with regard to testosterone, though contrary to that of Schumann, is in agreement with the report of Gaunt et al. 8 4. None of the experimental procedures led to any marked change in the maximum tension developed by the muscle.