Obstruction of Splenic Vein Increases Weight of Stomach and Predisposes to Erosion or Ulcer. ∗

Conclusions

1. Partial obstruction to the venous outflow from the stomach increases its weight in rabbits and dogs. 2. Esophageal varices can be produced by portal or splenic vien obstruction and, when histamine-inbeeswax is given to such animals, esophageal and gastric erosions and bleeding are produced. 3. Portal or splenic vien obstruction abets the ulcer diathesis.