Relationship of Carotid and Aortic Mechanisms to Digitalis Emesis. ∗

Conclusion

Vomiting initiated by digitoxin is not abolished by removal of the carotid bodies and sinuses and by denervation of the aortic mechanisms. Assumign the mechanism to be relex in nature, the site of origin of the impulses causing digitalis vomiting is still undetermined. The possibility remains that afferent impulses may be set up in a structure or structures not yet eliminated. It is perhaps more probable that impulses may arise from any one of several structures all of which would have to be denervated in the same animal to abolish the emetic response to digitalis.