Abstract
Summary
Six patients recovering from the acute febrile reaction of severe pneumococcic lobar pneumonia were given salt-poor human albumin intravenously. Electrophoretic analyses of the plasma proteins showed significant increases in the albumin concentration, together with reduction in globulins, particulary alpha-globulin, following this therapy. Simplified nitrogen balance studies showed retention of more protein than could be accounted for by the amount of albumin aIone. Another patient with shock related to serious heart diseasv succumbed from pulmonary edema shortly after the administration of albumin. The secondary cardio-respiratory effects of albumin therapy were investigated in 5 patients.
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