Intratesticular Versus Subcutaneous Transplantation of Brown-Pearce Tumor in New Zealand Whites

Summary and Conclusions

Standard values were compiled for the Brown-Pearce tumor in New Zealand white male rabbits, 42 being inoculated intratestieularly and 66 subcutaneously. The breed was highly resistant to subcutaneous inoculation, (mortality, 13.6%; metastatic foci, 3.2; metastatic tumor 13.1 cc per animal inoculated) and susceptible to intratesticular inoculation (mortality 62.7%, metastatic foci 11.4 and metastatic tumor 90.5 cc per animal inoculated). Between 40 and 60 days after intratesticular inoculation the mortality curve continued to rise at about the same rate as between 20 and 40 days. This was in contrast to the immune or resistance reaction which seemed to set in between 40 and 60 days following subcutaneous inoculation of this breed, or following intratesticular inoculation of most other breeds.