Lipotropic Activity of Various Compounds Under Standardized Conditions.

Summary

A representative group of substances, previously reported to be lipotropically active, have been tested. under standardized condtitions. Under the present experimental conditions and in the amounts fed, S-ethylcysteine did not decrease the level of the liver lipids, cystine betaine and S-methylcysteine exhibited a slight activity of questionable significance, inositol, dimethyl sulfide and S-methylisothiourea sulfate were of intermediate activity, and betaine and triethylcholine had approximately the activity of choline. Lipociac, at the 1% dietary level, was highly active lipotropically and stimulated growth to a greater degree than any of the other compounds tested. S-methylisothiourea sulfate depressed the growth rate.