Normal and Seizure Levels of Lactate,Pyruvate and Acid-Soluble Phosphates in the Cerebellum and Cerebrum. ∗

Summary

Lactic acid, pyruvic acid, inorganic phosphorus, phosphocreatine, and ATP-ADP were determined in liquid air fixed brains of normal and convulsed cats. In normal brains the levels in cerebellum and cerebrum were approximately the same. In convulsed brains, however, the lactic acid increases were much smaller and phosphocreatine levels were higher in cerebellum than in cerebrum despite the fact that seizure activity was approximately of equal intensity in both parts.