Detection of Mumps Virus in Mice Sacrificed at Different Periods of Time after Injection

Summary

Mumps virus administered to mice intraperitoneally or intranasally appears within an hour in the lungs, liver, spleen, and to a lesser extent in the brain (in the latter case after intraperitoneal injection only.) Sojourn of viable virus in organs where found is short. Testes, pancreas, heart muscle, and blood were found not to contain virus at any time. Mice used in these tests of mumps virus did not exhibit symptoms of toxicity at all comparable to mice injected at different times in the past with influenza virus, although these 2 viruses are somewhat similar otherwise.