Abstract
Summary
The steroid Δ1 deoxycorticosterone acetate will maintain adrenalectomized immature rats for 20 days with dosages of 0.25 mg and 0.5 mg and will increase daily body weight 1 and 2 g respectively. Activity is approximately 1/8 to 1/10 that of deoxycorticosterone acetate. Liver water content was unchanged in maintained adrenalectomized rats and the relative liver protein content of adrenalectomized rats receiving Δ 1 desoxycorticosterone acetate was comparable to that of normal rats. This steroid did not alter organ weights in normal immature female rats over a 10-day period except for a tendency toward liver weight increase.
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