Abstract
Summary
Guinea pigs inoculated intramuscularly with street virus can be protected by mustard inactivated fixed virus injected at the same time or 24 hours later, provided the virus has a high immunizing titer. These results give experimental proof that vaccine will protect after infection and also provide a test that could be used in evaluating vaccines for human use. If non-protecting amounts of vaccine or fixed virus are injected, the incubation period may be shorter and the death rate slightly higher than in the control animals receiving only street virus.
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