Abstract
Conclusions
1. Both ACTH and Cortisone therapy depress the gamma globulin and fibrinogen levels in the blood of patients with active rheumatoid arthritis and scleroderma.
2. Changes in these 2 blood proteins are responsible for the observed changes in the sedimentation rate.
3. At the present state of our knowledge, the sedimentation rate cannot be used as an index of the effectiveness of hormone therapy on the active disease process.
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