Abstract
Summary
Examination of 10 rats sacrificed 18 months after a single injection of 400 μc of radioactive iodine revealed the following changes in the thyroid gland: 1. Hürthle-like elements (previously reported by us in thyroids of rats sacrificed 8 months after a single I131 injection) were evident in the parenchyma of all glands. 2. Multiple adenomata, apparently benign in nature, were found in the thyroids of 2 rats. 3. Two types of anaplastic, nonencapsulated neoplasms, one of which was invading adjacent thyroid tissue, were also found in the thyroids of these 2 rats.
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