Abstract
Summary
1.0 mg ACTH was injected into rats for 8-10 days. Liver slices from these animals showed a decreased methylation of nicotinamide and an increased methylation of guanidoacetic acid. The methylation of homocysteine was unaffected. Tyrosine formation from phenylalanine was inhibited as was uric acid formation from xanthine. Urea production was normal. Endogenous ketone body production and the oxidation of octanoate was increased.
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