Abstract
Summary
Toxoplasma gondii has been propagated successfully in macrophage cultures of adult laboratory animals. The pattern of the interaction between the macrophages cultured in vitro from different animal species could be correlated with the susceptibility of the species to the infection with Toxoplasma. Macrophages cultured in vitro from animals actively immunized by injection with living Toxoplasma had an inhibitory effect on the intracellular multiplication of these parasites. This effect was increased by the presence of immune serum which had a high titer of cytoplasm-modifying antibodies.
Get full access to this article
View all access options for this article.