Abstract
Summary
In the glomerular stroma and arterioles of non-diabetic persons treated with cortisone an abnormal substance was found with ultraviolet absorptive properties indistinguishable from those of the nodules of intercapillary glomerulosclerosis. Histochemical properties of the material suggest that it is a mucopolysaccharide complex. The evidence is considered that implicates cortisone as one factor in the development of human diabetic intercapillary glomerulosclerosis.
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