Lack of Hematopoiesis in Tail Bones Transposed to Abdominal Cavity of Hypophysectomized Rats. ∗

Summary

Thirty-seven of 41 normal female rats, in which the ends of the tails were transposed into the abdominal cavity, showed a stimulation of hematopoiesis in the intra-abdominal vertebrae. Developing cells of all 3 types—erythroid, myeloid and megakaryocytes—were observed in these animals. In similarly treated hypophysectomized female rats only 1 of 16 animals showed any indication of response. The experiment provides another example of the depressed hematopoietic potential of the hypophysectomized rat.