Further Studies of Regioselective Alkoxydehalogenation of 2,4-dichloroquinolines,2,6-dichloropyridine and 2,4-dichloronitrobenzene

Abstract

A comparison of regioselective (solid sodium alkoxide/toluene) and standard (alcoholic alkoxide solution) alkoxydehalogenation reactions with a series of 2,4-dichloroquinolines and with 2,6-dichloropyridine and 2,4-dichloronitrobenzene, with product analysis by NMR spectroscopy, is reported.

Keywords

nucleophilic substitution quinolines pyridines alkoxydehalogenation

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