Enaminones as building blocks in heterocyclic synthesis. Synthesis of polyfunctionally substituted 3-azolylpyridines and azolylazoloazines by thermal and microwave heating

2-Azolyl-3-enaminones (la–e) react with ethyl cyanoacetate to yield 2-pyridones or 2-aminopyridines depending on the reaction conditions. The reaction of la with benzoylacetonitrile afforded a pyridine derivative. Condensation of heteroaromatic aminoazoles with la–e afforded azolopyrimidines. HMBC and NOE difference experiments assisted the assignment of structures to the reaction products.