Abstract
Potassium [14C]cyanide was first hydrolysed to potassium [14C]formate with dilute alkali under microwave (1300 W) irradiation for 8 min in a sealed glass ampoule. Potassium [14C]formate was then esterified with triethyl orthophosphate under microwave irradiation for 20 min to furnish ethyl [14C]formate having high specific radioactivity (50 mCi/mmol) in an yield of 98%.
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References
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