Efficient Synthesis of Terpyrrole Derivatives by a Pseudo-Five-Component Reaction between Pyrrole,β-Enaminocarbonyls and Arylglyoxals

Pyrrole reacts with arylglyoxal monohydrates and enaminoketones or enaminoesters in alcoholic media in the presence of FeBr₃ as a catalyst to produce 2,5-bis(1H-pyrrol-2-yl)-1H-pyrrole derivatives in high yields as the only product. Reactions are clean and products are isolated by simple filtration.