Abstract
The present study evaluates the whole blood filterability index (WB-FI) and the washed red blood cell filterability index (WRBC-FI) in 21 chronic cerebrovascular insufficiency (CCVI) patients and in 36 control subjects. Althoug no significant differences were found in the mean values of the two groups, approximately 30% of the patients had a decreased WB-FI. Of the 7 CCVI patients who showed reduced WB-FI, this decrease could be attributed to erythrocyte deficiency in only two of the cases. Of the 21 CCVI patients, pentoxifylline (POX) was administered to 9, dipyridamole (DIP) to 6 and POX+DIP to another 6.
The changes in WB-FI were evaluated 7, 15 and 45 days after treatment was begun. POX and DIP administered separately favoured WB-FI at 15 and 7 days respectively, but when administered together, WB-FI only increased slightly on the 45th day.
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