RELATIONSHIP BETWEEN ACUPUNCTURE-INDUCED IMMUNITY AND THE REGULATION OF CENTRAL NEUROTRANSMITTER SYSTEM IN RABBITS ---II. EFFECT OF THE ENDOGENOUS OPIOID PEPTIDES ON THE REGULATION OF ACUPUNCTURE-INDUCED IMMUNE REACTION

Abstract

By injecting Naloxone, the T-lymphocyte transformation was reduced markedly. When the Naloxone plus electro-acupuncture were used together, it was not reduced but was still lower than it was when only electro-acupuncture was used. This explained why Naloxone could reverse the function by which electro-acupuncture promoted the T-lymphocyte transformation, and the endogenous opioid in the brain promoted the immune reaction. Through promoting the release of the endogenous opioid in the brain, electro-acupuncture raised the T-lymphocyte transformation function.

Using electro-acupuncture when naloxone antagonized morphine, the T-lymphocyte transformation function was still promoted markedly. The mechanism could be that electro-acupuncture excited the function of the endogenous opioid system in the brain. In acupuncture immune reaction, the relationship between the endogenous opioid and catecholaminergic systems was explored.

Keywords

Morphine Naloxone Electro-acupuncture(EA)Immune reaction T-lymphocyte transformation Endogenous opioid Lysozyme Rabbit

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