We present a unique case of a 42-year-old gentleman with newly diagnosed Graves’ disease and isolated right ventricular failure. Extensive evaluation to include echocardiogram and cardiac catheterization were negative for significant pulmonary hypertension or coronary artery disease as potential etiologies. Hyperthyroid induced vasospasm is a rare but reported clinical entity that serves to be a clinical and diagnostic dilemma.
MoliternoD., DeBoldC.R., RobertsonR.M.Case report: coronary vasospasm-relation to the hyperthyroid state.Am J Med Sci1992; 304: 38–42.
2.
PatelR., PetersonG., RohatgiA.Hyperthyroidism-Associated Coronary Vasospasm with Myocardial Infarction and Subsequent Euthyroid Angina.Thyroid2008; 18: 273–6.
3.
LinT., SuH., VoonW.Unstable Angina with Normal Coronary Angiography in Hyperthyroidism: A Case Report.The Kaohsiung J Med Sci2005; 21: 29–33.
4.
OngP., AthanasiadisA., HillS.Coronary Artery Spasm as a Frequent Cause of Acute Coronary Syndrome: The CASPAR (Coronary Artery Spasm in Patients with Acute Coronary Syndrome) Study.J Am Coll Cardiol2008; 52: 523–7.
5.
NakchbandiI.A., WirthJ.A., InzucchiS.E.Pulmonary Hypertension Caused by Graves’ Thyrotoxicosis: Normal Pulmonary Hemodynamics Restored by 131I Treatment.Chest1999; 116: 1483–5.
6.
HaranM., LodhaA., GroopmanJ.Pulmonary Hypertension in Grave's Disease.Endocrinologist2008; 18: 273–4.
7.
WasseemR., MazenE., WalidS.Hyperthyroidism: A Rare Cause of Reversible Pulmonary Hypertension.Am J Med Sci2006; 332: 140–1.
8.
ViraniS.S., MendozaC.E., FerreiraA.C.Graves’ Disease and Pulmonary Hypertension: Report of 2 Cases.Tex Heart Inst J2003; 30: 314–5.
9.
NapoliR., BiondiB., GuardasoleV.Impact of Hyperthyroidism and its Correction on Vascular Reactivity in Humans.Circulation2001; 104: 3076–80.
10.
CohenJ., SchattnerA.Right heart failure and hyperthyroidism: a neglected presentation.Am J Med2003; 115: 76–7.
11.
WoeberK.A.Thyrotoxicosis and the heart.N Engl J Med1992; 327: 94–8.
