Assessment of Modifications in Thickness,Curvatures,and Volume upon the Cornea Caused by Disposable Soft Contact Lens Wear

Abstract

Purpose

To assess the effect of different disposable soft contact lenses on several corneal parameters–-thickness, anterior and posterior curvature, and volume–-by means of a Scheimpflug imaging-based device (Pentacam HR). Diurnal variations of these parameters were taken into account.

Methods

Twenty-one young, healthy subjects wore 4 different types of daily disposable soft contact lenses on 4 different days: Dailies AquaComfort Plus, SofLens, Dailies Total1, and Acuvue TruEye. The lenses had different material and water content. Pachymetry and curvature maps and corneal volume values were obtained using the Pentacam HR twice a day: one before putting the lens on and one after an 8-hour period of contact lens wear. Measurements were also taken without any contact lenses being worn.

Results

Regarding corneal thickness, the lens with the most similar behavior to the naked eye scenario was the Dailies Total1, causing a thickening of 0.2 ± 0.1% in the central zone and 0.6 ± 0.2% in the periphery. All 4 lenses caused a slight but not significant flattening in the anterior corneal curvature, whereas the posterior corneal curvature only experienced a significant but small steepening with the SofLens. The use of these lenses increased corneal volume slightly.

Conclusions

Variations in corneal parameters seem to depend on the type of contact lens used (material, oxygen transmissibility, water content). However, the magnitude of the changes introduced by the use of soft contact lenses over the 8-hour period was small and probably not large enough to influence either visual acuity or comfort.

Keywords

Contact lens Corneal curvature Corneal thickness Corneal volume

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References

Yebra-Pimentel

Giráldez

M.J.

Arias

F.L.

. Rigid gas permeable contact lens and corneal topography. Ophthalmic Physiol Opt. 2001; 21: 236–42.

Schwallie

J.D.

Barr

J.T.

Carney

L.G.

. The effects of spherical and aspheric rigid gas permeable contact lenses: corneal curvature and topography changes. Int Contact Lens Clin. 1995; 22: 67–79.

Schornack

. Hydrogel contact lens-induced corneal warpage. Cont Lens Anterior Eye. 2003; 26: 153–9.

Arranz

Gonzalez-Garcia

M.J.

Galarreta

D.J.

Cisneros

A.B.

Calonge

Herreras

J.M.

. Low water content hydrogel contact lenses (HCL) induce corneal irregularity. Invest Ophthalmol Vis Sci. 2003; 44: ARVO E-Abstract 3701.

Alba-Bueno

Beltran-Masgoret

Sanjuan

Biarnés

Marín

. Corneal shape changes induced by first and second generation silicone hydrogel contact lenses in daily wear. Cont Lens Anterior Eye. 2009; 32: 88–92.

Tyagi

Collins

Read

Davis

. Regional changes in corneal thickness and shape with soft contact lenses. Optom Vis Sci. 2010; 87: 567–75.

Snyder

A.C.

Schoessler

J.P.

. Corneal thickness changes associated with daily and extended contact lens wear. Am J Optom Physiol Opt. 1983; 60: 830–8.

Kaluzny

J.J.

Orzalkiewicz

Czajkowski

. Changes of corneal thickness in patients wearing frequent-replacement contact lenses. Eye Contact Lens. 2003; 29: 23–6.

Cankaya

A.B.

Beyazyildiz

Ileri

Ozturk

. The effect of contact lens usage on corneal biomechanical parameters in myopic patients. Cornea. 2012; 31: 764–9.

10.

Alonso-Caneiro

Shaw

A.J.

Collins

M.J.

. Using optical coherence tomography to assess corneoscleral morphology after soft contact lens wear. Optom Vis Sci. 2012; 89: 1619–26.

11.

Reynolds

D.R.

Poynter

III . Diurnal variation in central corneal curvature. Am J Optom Arch Am Acad Optom. 1970; 47: 892–9.

12.

Cronje

Harris

W.F.

. Short-term keratometric variation in the human eye. Optom Vis Sci. 1997; 74: 420–4.

13.

Handa

Mukuno

Niida

Uozato

Tanaka

Shimizu

. Diurnal variation of human corneal curvature in young adults. J Refract Surg. 2002; 18: 58–62.

14.

Read

S.A.

Collins

M.J.

Carney

L.G.

. The diurnal variation of corneal topography and aberrations. Cornea. 2005; 24: 678–87.

15.

Armstrong

R.A.

. Statistical guidelines for the analysis of data obtained from one or both eyes. Ophthalmic Physiol Opt. 2013; 33: 7–14.

16.

Lackner

Schmidinger

Pieh

Funovics

M.A.

Skorpik

. Repeatability and reproducibility of central corneal thickness measurement with Pentacam, Orbscan, and ultrasound. Optom Vis Sci. 2005; 82: 892–9.

17.

O'Donnell

Maldonado-Codina

. Agreement and repeatability of central thickness measurement in normal corneas using ultrasound pachymetry and the OCULUS Pentacam. Cornea. 2005; 24: 920–4.

18.

Shankar

Taranath

Santhirathelagan

C.T.

Pesudovs

. Anterior segment biometry with the Pentacam: comprehensive assessment of repeatability of automated measurements. J Cataract Refract Surg. 2008; 34: 103–13.

19.

Chen

Lam

A.K.

. Intrasession and intersession repeatability of the Pentacam system on posterior corneal assessment in the normal human eye. J Cataract Refract Surg. 2007; 33: 448–54.

20.

Mertz

G.W.

. Overnight swelling of the living human cornea. J Am Optom Assoc. 1980; 51: 211–4.

21.

Read

S.A.

Collins

M.J.

. Diurnal variation of corneal shape and thickness. Optom Vis Sci. 2009; 86: 170–80.

22.

Harper

C.L.

Boulton

M.E.

Bennett

. Diurnal variations in human corneal thickness. Br J Ophthalmol. 1996; 80: 1068–72.

23.

Feng

Varikooty

Simpson

T.L.

. Diurnal variation of corneal and corneal epithelial thickness measured using optical coherence tomography. Cornea. 2001; 20: 480–3.

24.

du Toit

Vega

J.A.

Fonn

Simpson

. Diurnal variation of corneal sensitivity and thickness. Cornea. 2003; 22: 205–9.

25.

Boote

Dennis

Newton

R.H.

Puri

Meek

K.M.

. Collagen fibrils appear more closely packed in the prepupillary cornea: optical and biomechanical implications. Invest Ophthalmol Vis Sci. 2003; 44: 2941–8.

26.

Müller

L.J.

Pels

Vrensen

G.F.

. The specific architecture of the anterior stroma accounts for maintenance of corneal curvature. Br J Ophthalmol. 2001; 85: 437–43.

27.

Van Horn

D.L.

Doughman

D.J.

Harris

J.E.

Miller

G.E.

Lindstrom

Good

R.A.

. Ultrastructure of human organ-cultured cornea. II. Stroma and epithelium. Arch Ophthalmol. 1975; 93: 275–7.

28.

Cristol

S.M.

Edelhauser

H.F.

Lynn

M.J.

. A comparison of corneal stromal edema induced from the anterior or the posterior surface. Refract Corneal Surg. 1992; 8: 224–9.

29.

Sedaghat

M.R.

Sharepoor

Hassanzadeh

Abrishami

. The corneal volume and biomechanical corneal factors: Is there any correlation? J Res Med Sci. 2012; 17: 32–39.

30.

Odenthal

M.T.

Nieuwendaal

C.P.

Venema

H.W.

Oosting

Kok

J.H.

Kijlstra

. In vivo human corneal hydration control dynamics: a new model. Invest Ophthalmol Vis Sci. 1999; 40: 312–9.

31.

O'Neal

M.R.

Polse

K.A.

. In vivo assessment of mechanisms controlling corneal hydration. Invest Ophthalmol Vis Sci. 1985; 26: 849–56.

32.

Liu

Pflugfelder

S.C.

. The effects of long-term contact lens wear on corneal thickness, curvature, and surface regularity. Ophthalmology. 2000; 107: 105–11.

33.

Moezzi

A.M.

Fonn

Simpson

T.L.

Sorbara

. Contact lens-induced corneal swelling and surface changes measured with the Orbscan II corneal topographer. Optom Vis Sci. 2004; 81: 189–93.

34.

Martin

Izquierdo

Saber

. Investigation of posterior corneal curvature in CL-induced corneal swelling. Cont Lens Anterior Eye. 2009; 32: 288–93.

35.

Hirji

N.K.

Larke

J.R.

. Corneal thickness in extended wear of soft contact lenses. Br J Ophthalmol. 1979; 63: 274–6.

36.

Schoessler

J.P.

Barr

J.T.

. Corneal thickness changes with extended contact lens wear. Am J Optom Physiol Opt. 1980; 57: 729–33.

37.

Bonanno

J.A.

Polse

K.A.

. Central and peripheral corneal swelling accompanying soft lens extended wear. Am J Optom Physiol Opt. 1985; 62: 74–81.

38.

Bonanno

J.A.

Nyguen

Biehl

Soni

. Can variability in corneal metabolism explain the variability in corneal swelling? Eye Contact Lens. 2003; 29(Suppl): S7–S9, discussion. S26–9, S192–4.

39.

Hess

R.F.

Garner

L.F.

. The effect of corneal edema on visual function. Invest Ophthalmol Vis Sci. 1977; 16: 5–13.

40.

Sarver

M.D.

Polse

K.A.

Baggett

D.A.

. Intersubject difference in corneal edema response to hypoxia. Am J Optom Physiol Opt. 1983; 60: 128–31.