New pharmacologic agents facilitated and improved the overall management of endometriosis also in case of pregnancy desire. The present study aimed to investigate the efficacy of a food integrator on painful symptoms in endometriotic women looking for pregnancy.
Methods
This is a pilot study including a group of patients (n = 20) with a previous surgical diagnosis of endometriosis and painful recurring symptoms. A daily dose of two pills of a food integrator containing curcumin, quercetin, hyaluronic acid and chondroitin sulphate (Ialuril Soft gels IBSA, Italy) was self-administered for 12 weeks. Painful symptoms were evaluated by a visual analog scale (VAS) system before and after the end of treatment.
Results
A significant reduction in the intensity of dysmenorrhea (p<0.001), chronic pelvic pain (p<0.001), and dysuria (p<0.001) compared with the severity of these symptoms before the administration was showed.
Conclusions
In all patients, the efficacy of Ialuril soft gels was shown after 12 weeks of treatment for dysmenorrhea, chronic pelvic pain and dysuria, thus providing an alternative option for women seeking pregnancy. In the future, further controlled trials will be required, with a larger population and longer follow-up period, to confirm these initial encouraging results.
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