Approximately 1.3% of women will be diagnosed with ovarian cancer at some point
during their lifetime. The association between endometriosis and cancer has been
described in numerous published studies. However, the lifetime risk for ovarian
cancer is low in the general population and it does not change in women with
endometriosis. Endometrioid and clear-cell ovarian tumors appear to be
associated with pelvic endometriosis. Apparently, women with
endometriosis-associated ovarian cancer differ from non-endometriosis-associated
ovarian cancer patients in their clinical characteristics. This review
summarizes the epidemiologic and molecular evidence and also the clinical
implications of the association between endometriosis and ovarian cancer.
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