Bulky Mesonephric Adenocarcinoma of the Uterine Cervix Treated with Neoadjuvant Chemotherapy and Radical Surgery: Report of the First Case

Abstract

Aims and background

Malignant mesonephric adenocarcinoma of the uterine cervix is a rare occurrence with few cases described in the literature. Although surgery seems to be effective in the treatment of early-stage tumor, no cases describing outcomes of locally advanced stage are available.

Methods

We report the first case of a patient with International Federation of Obstetrics and Gynecologists stage IIB mesonephric adenocarcinoma undergoing neoadjuvant chemotherapy and radical surgery.

Conclusions

Despite the inherent limitation of a single description of a case, our experience supports the utilization of neoadjuvant chemotherapy in patients with malignant mesonephric adenocarcinoma of the uterine cervix. Further prospective multi-institutional studies are needed.

Keywords

Advanced stage Cervical carcinoma Mesonephric adenocarcinoma Neoadjuvant chemotherapy

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