26:T552,

The formation of antimicrobial regenerated cellulose fibers using an ionic liquid solvent, 1-butyl-3-methylimidazolium chloride, and silver nanoparticles was studied. The cellulose preparation and dispersion efficiency of the silver nanoparticles in the solvent were evaluated via scanning electron microscope and transmission electron microscopy in terms of different processing conditions. The influence of silver nanoparticles on regenerated cellulose fiber crystallization and strength was examined using a wide angle X-ray diffractometry and tensiometry, respectively. The bioactive efficacy of the cellulose/nano-silver fiber was tested in accordance with the standard method of ASTM E 2149-10. The cellulose/nano-silver fibers were bioactive and killed Escherichia coli almost completely without any leaching problems. The addition of nano-silver significantly increased the cellulose fiber tensile strength and modulus with an insignificant reduction in fiber elongation, and a slower thermal decomposition rate, evidenced by increased fiber crystallinity. Higher processing temperatures improved the nano-silver dispersion efficiency. The final nano-silver suspension in the regenerated cellulose matrix was composed of scattered clusters with an average size of 700 nm and a distribution density of 14,098 mm⁻².

27:T4a4,

The addition of calcium phosphate fillers or antimicrobials to bone cements seems to produce inferior materials. In this study, a two-solution bone cement composite was designed for high viscosity and high pseudoplasticity to improve injection and mitigate the risk of extravasation. By pre-mixing these cements, the fillers are incorporated into the matrix and should not detrimentally affect the performance properties. To expand the functionality of this cement system, the addition of bioactive and antimicrobial phases were explored. Brushite and chlorhexidine were used as calcium phosphate filler and the antimicrobial phase, respectively. By controlling the free radical quenching mechanism provided by the chlorhexidine molecule, it was possible to achieve high polymer conversion rates. This phenomenon led to cement strength retention while successfully preventing microbial proliferation in an environment exposed to the cement surface. Based on these results, two-solution cement composite prepared with high concentrations of brushite and chlorhexidine diacetate salt hydrate may provide an attractive bioactive and antimicrobial cement for load-bearing applications.

28:T4a8,

In this study, polyurethane urea was surface-modified to elevate cell recognition through immobilization of bioactive gelatin. The poly(urethane urea) was synthesized using poly(ε-caprolactone) diol in the absence of a chain extender. The synthesized polyurethane urea was then functionalized with gelatin (gelatin-grafted poly(urethane urea)) via aminolysis. Chemical changes at the polyurethane urea surface were monitored using titration, water contact angle. Fourier transform infrared, and zeta potential measurements. Significantly larger amounts of gelatin were grafted on the polyurethane urea surface compared to those previously reported for poly(ε-caprolactone) diol (three times more) and polyurethanes (two times more), while the mechanical properties were not compromised. Proliferation of human adipose–derived mesenchymal stem cells on the polyurethane urea and the gelatin-grafted polyurethane urea was evaluated through MTT assay. Although both samples enhanced human adipose–derived mesenchymal stem cells’ proliferation, gelatin-grafted polyurethane urea supported human adipose–derived mesenchymal stem cells’ proliferation at a remarkably higher rate.

29:T538,

Trehalose cinnamoyl esters (TCs) were synthesized by esterification of trehlaose with cinnamoyl chloride. Two TCs with different degrees of substitution were synthesized, and trehalose cinnamoyl ester thin film-coated glass plates were prepared by a dip-coating method. Photocuring of the TCs was confirmed by ultraviol