Journal of Diagnostic Medical Sonography

Various indices have been introduced for estimating sonographic gestational age and have demonstrated varied diagnostic accuracy. The aim of this study was to evaluate the correlation of fetal kidney length (FKL) with some other traditional measurement parameters in determining an accurate gestational age.

In this prospective study, healthy pregnant women, who had completed a scheduled and routine obstetrical sonogram, were included. During the sonogram, the measurement indices, biparietal diameter (BPD), abdominal circumference (AC), crown rump length (CRL), head circumference (HC), femur length (FL), and FKL were analyzed. The obstetrical measurements had been taken every 4 weeks from the 20th week of the pregnancy, until the end of the pregnancy (e.g., 20th, 24th, 28th, 32nd, 36th, 40th weeks). After data collection, the measurement data were analyzed with SPSS software.

There were significant (P < .05) high strength of associations between FKL and the routine measurements of BPD (r = 0.668), AC (r = 0.770), CRL (r = 0.792), HC (r = 0.791), and FL (r = 0.803).

These results suggest possible significant positive relationships between FKL and BPD, AC, CRL, HC, and FL. It can be assumed that FKL might be a suitable index for determining gestational age especially in the late second and third trimester, when other measurement indices are less accurate.

Ultrasonography (US) and fine-needle aspiration biopsy (FNAB) play an important role in the diagnosis of thyroid nodules. The primary aim of this study was to evaluate the relationship between American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) and the Bethesda system, based on final cytopathology.

The cases that underwent thyroidectomy, due to a nodule, between May 2019 and May 2021 were retrospectively imaged. Of those cases, 73 patients were included in the study. The obtained data included ACR TI-RADS and the Bethesda system scores for nodules.

According to Spearman correlation, a very strong positive relationship was found between the Bethesda scoring system and ACR TI-RADS scores (ρ = 0.832, P < .0001). A 94.4% sensitivity and 65.4% specificity were found in 16 patients with a Bethesda score of 3 and TR3 based on final pathology (P < .001). And a sensitivity of 77.3% and specificity of 51.5% were found in 17 patients, with a Bethesda score 4 and TR4 (P < .001). Finally, a sensitivity of 55.6% and specificity of 50.0% were found in 17 patients with a Bethesda score 6 and TR5 (P < .001).

The routine use of the ACR TI-RADS classification in thyroid nodules could be useful in preventing unnecessary FNABs. It could be effective in minimizing complications secondary to FNAB and thyroidectomy and reducing costs.

The aim of this study was to determine the efficiency of a fat-lesion histographic analysis (FLHA) to make a benign-malignant differentiation, for patients with a breast mass. In addition, it was important to examine the relationship between FLHA rates and Breast Imaging–Reporting and Data System (BI-RADS) scoring.

This was a retrospective study conducted by examining the breast ultrasonograms (BUS) and histopathologic data of 76 women, having at least one solid breast mass. The patients were grouped according to their histopathologic diagnoses and BUS BI-RADS scores. The recorded digital gray-scale images were transferred to a workstation to quantitatively measure tissue echogenicity. The breast masses and adjacent adipose tissue were evaluated using the ImageJ analysis program, and gray-scale histographic analysis values were generated. The FLHA rate was determined by dividing the fat tissue histographic value by the mass-lesion histographic value. Statistical analysis was performed using this value as well as the patients’ histopathologic data and BUS BI-RADS score.

A complementary effect was noted using FLHA rates with the BUS BI-RADS criteria, and a statistically significant difference was detected between benign and malignant histopathology groups (P < .001). Similarly, the malignant histopathologic diagnosis with BI-RADS 4 and benign histopathologic diagnosis with BI-RADS 4 groups were related (P < .001). The correlation between BI-RADS criteria and FLHA rates demonstrated a significant difference between BI-RADS 3 and BI-RADS 5 (P < .001), and BI-RADS 4 and BI-RADS 5 for FLHA rates (P = .002).

It was determined that using the FLHA rate was a complement to the BUS BI-RADS criteria. In this cohort, there was a statistically significant difference in predicting possible malignancy in all BI-RADS classes.

The American College of Radiology Thyroid Imaging Reporting and Data System (ACR TI-RADS) is a reporting system for thyroid nodules detected with sonography and proposed by the ACR. The scoring of punctate echogenic foci (PEF) increases the TI-RADS score and leads to a biopsy of many thyroid nodules, otherwise found clinically. The aim of this study was to assess the risk of malignancy for mixed and solid nodules, with and without PEF, and cytologic correlation.

Thyroid sonograms and ultrasound-guided thyroid biopsies were performed, at a University of Iowa Hospitals & Clinics for 105 patients, during July 2019 to June 2020. All these retrospective clinical studies were reviewed against the cytologic examinations.

Based on the 189 thyroid nodule biopsies reviewed, 82.5% were benign compared with 17.5% malignant lesions. A solid nodule composition was noted in 35.2%, and had a higher risk for malignancy, compared with 7.7% of the mixed nodules. There was a 33.3% incidence of malignancy for solid nodules with PEF, compared with 35.8% of lesions lacking PEF. For mixed nodules, 6.2% nodules demonstrated PEF and 7.7% of nodules, without PEF, were malignant.

In this cohort, solid nodules had a higher risk of malignancy than mixed nodules. PEF did not increase the risk of malignancy in either solid or mixed thyroid nodules, in these patients. These findings would suggest that existing guidelines may overestimate the value of PEF in scoring, as well as determining which thyroid nodules require biopsy.

During acute renal colic due to nephrolithiasis, a new sonographic diagnostic sign was noted, called “a swinging kidney.” This term was given due to a characteristic anteroposterior “rolling” movement of the kidney. A preliminary investigation was conducted to evaluate the correlation between this new diagnostic sign and nephrolithiasis.

An exploratory observational investigation was conducted on adult patients who accessed an emergency medicine department, with acute renal colic, between June 1, 2019, and October 31, 2019.

Thirty-seven patients were enrolled. The “swinging kidney” was present in 26 cases (70%). This sign was correlated with a stone’s diameter of less than 10 mm (χ²: 4.68; P = .031), and with a stone localization in the juxtavesical ureter tract site (χ²: 10.83; P = .029). Spontaneously stone expulsion was correlated with the presence of the “swinging kidney” (χ²: 4.66; P = .031); with the minor degree of hydronephrosis (χ²: 16.82; P = .0008), and with a distal localization of the stone (χ²: 25.11; P = 1:47 × 10⁻⁵).

The “swinging kidney” may be a promising diagnostic sign that could be useful in diagnosing nephrolithiasis besides the other indirect sonographic signs. This new diagnostic sign could have a prognostic role.

The aim of this study was to suggest a new sonographic sign, which could be helpful in the determination of chorionicity in twin pregnancies, during the second and third trimesters.

This was a retrospective study evaluating the sonographic images of 50 women with twin pregnancy. Out of 50 twin pregnancy case reviewed, only 27 were included. Those patient cases that were included were scanned by a single radiologist. The presence of a hypoechoic cleft, in the thickness of placental bulk, could be detected in all of the dichorionic pregnancy cases. This sonographic appearance was referred to as the “cleft sign.”

The “cleft sign” was present in all the dichorionic diamniotic (DC-DA) twin pregnancy cases, but no similar appearance was seen in the monochorionic diamniotic (MC-DA) twins. Considering this sign, the radiologist was able to correctly diagnose the chorionicity of all 24 patients in the second and third trimester.

The findings of the present study suggest a possible role for this newly identified “cleft sign.” This sonographic appearance is a hypoechoic cleft in the thickness of placenta, of dichorionic pregnancies, as an indicator of DC twin pregnancy. In this retrospective case analysis, the “cleft sign” was diagnostically significant in the second and third trimesters.