Nutrition and Health

Deficiencies in DHA/EPA are widespread, but not widely recognised. The scale of the problem is difficult to assess, because targets for consumption vary and intakes are poorly measured, but most people in most countries eat too little. The principal policies to correct the shortfalls have been educational programmes urging people to eat more fish. Two problems limit this approach: many do not like fish; and there are not enough fish available if everyone ate recommended levels. One pragmatic alternative is to start with the popular foods people actually eat, then fortify them with DHA/EPA. The paper discusses technical options for doing this, and three problems: the scale of sales, the use of inappropriate forticants, and the costs. The key to reducing costs lies in obtaining new, larger, sustainable and cheaper sources of DHA/EPA. Major efforts to achieve this are underway the genetically modified crops and new sources of algae. The public health goal is affordable fortified foods consumed by billions, not just affluent, health-conscious minorities. It is a strategy for nutritional improvement without dietary change.

Although our continuing evolution can never achieve our perfection, we long for our children’s birth and health to be near-perfect. Many children are born healthy, though fewer than is possible. Birthing and health rapidly improved generally due to modern housing, sanitation and medicine, as well as birth interventions. Arguably interventions have exceeded the optimal level, without enough regard for natural physical and intuitive resources. Conception, often too easy, receives too little personal preparation unless a couple has problems. Nurturing the health of sperm and ovum seems hard to focus on, yet is needed by both parents – and even by the four grandparents. What are the key factors? Positive: The fields of hormones/emotions and of nutrition/metabolism. Negative: stress, poor nutrition, toxins, diseases; much being due to poverty. Positive and negative both have structural and also epigenetic effects. Interventions, essential or inessential, are seldom without negative side effects. Health can best, and most economically, be generated at the beginning of life, through healthy conception, gestation and birth. Understanding prime needs improves initial health. It also informs therapy of any early-life problems. Healing is therefore more efficient when transgenerational, and much more powerful than individual healing. My vision of healing is safeguarding our evolution in progress. Children's choices – eating, exercise, emotional attitudes and relationships – are already profoundly affecting any children they may have, their mental and physical health. The most practical starting point seems to be educating boys as well as girls. Childhood is therefore the time to educate them in choices. The correction of often unnoticed problems– nutrient deficits, toxins, uro-genital disease – has enabled nearly nine out of ten couples to bear fully healthy babies, even following severe problems – infertility, miscarriages, stillbirths and malformations. Correcting problems before conception prevents both structural faults and wrong setting of gene-switches. Children's habits set. Once courting most are preoccupied and many pregnant unintentionally. Childhood is the time to be adopting a healthy lifestyle, the way to healthy babies The mother's nutritional and emotional status throughout pregnancy continues to affect her child's future physical and mental health, behaviour and ability. Before conception a woman needs to build her appropriate body stores – vitamins and minerals, proteins, docosahexaenoic acid. Before bearing another child, a replenishment time of 3 years is desirable. A return to childbearing in the 20s and early 30s could reduce risks that have risen with the recent shift towards conception by school children and by women in their late 30s or more. Governments, schoolteachers, health professionals, need to adopt this policy of transgenerational health. Empowerment with knowledge is the one way to fend off the growing pandemic of mental ill health and related disorders and to make the most of a nation's genetic potential. Financially there could be no better investment, let alone in enhancing people's lives. Childhood is the most appropriate time for education in this way to generating a healthy, able and peaceful human race. Essential to our amazing genetic systems are the resources of land, sea and air. We are one with our biosphere. We need urgently to follow up the vital work of Developmental Origins of Health and Disease, and of Far East initiatives in sea-bed and sea husbandry.

The Nutrition And Mental Performance In Children project of the European Union (NUTRIMENTHE) has added to the evidence that maternal diet influences mental performance in childhood. The biological mechanisms have been shown to be complex and to involve genetic variation, as indicated by the work linking genetic variation in the fatty acid desaturase gene cluster to the processing of fatty acids. The role played by a child’s diet also needs to be considered and this question is being addressed through the inclusion of post-natal intervention studies in the NUTRIMENTHE project's research plan. This paper summarises progress.

Adolescence is often associated with exploring boundaries, rapid growth, hormones and pimples. A stable feature of this turbulent age is that these young people are highly over-represented in the criminal justice system. Adolescents account for disproportionate proportion of police-recorded crimes, and this seems to be a cross-cultural phenomenon. Furthermore, disaffected young people often have limited routine access to healthy foods and make poor food choices. These people form a large proportion of the prison population and there are concerns that insufficient attention is paid to their health. Hence their diet tends to be poor compared with international standards of dietary adequacy, which typically are set to protect the heart but not for optimal brain function. Thus, it has been posited that a poor diet may be a modifiable causal factor in antisocial behaviours. We tested what happened to the behaviour of violent young adult prisoners (18–21years) when nutrients missing from their diets were reinstated. We used food supplements as an analogue of a better diet because it provided the possibility of a placebo control. On a random basis, where neither the volunteers, prison staff nor researchers in the prison knew who was getting which type, 231 volunteers were given either placebo or real capsules containing broadly the daily requirements of vitamins, minerals and essential fatty acids. The number of proven offences committed by each prisoner was monitored before and while taking supplements. The result was that those who received the extra nutrients committed significantly (26.3%) fewer offences compared with placebos. Those consuming real supplements for at least 2 weeks committed 37% fewer (highly statistically significant) of the most serious offences, such as violence. These findings have been replicated by the Dutch Ministry of Justice; their double-blind study reported a 48% difference between groups. If these studies are widely replicated – and they need to be – we may have a simple and humane means to help reduce and prevent a significant proportion of violence and antisocial behaviour. This should also work in the community, because it is not about where you eat but what you eat. Indeed, criminal justice systems are often over-represented with ethnic minorities, but providing a more nutritious diet is never going to be discriminatory to these young people. The only risk is better health.

The modern Western diet bears little resemblance to the diet which forged the human genome over many million years. The change in basic food structure is operating to distort biology even before conception and into late years, with the epidemic of obesity and diabetes likely to lead to stroke, heart disease, and now dementia, being flagged as a consequence. In addition, mental ill health is overtaking all other burdens of ill health, and almost certainly has its roots in early disturbance of brain development. Whilst lifestyle will be playing its part, there can be little doubt that the common denominator is the aberrations in food development, predominantly in the last century. It seems it is time to reassess food policy. The principle of food production should be nutrition and human health. The globalisation of a food structure linked to such disorders and their appearance globally in response asks that steps be taken to protect other countries from making the same mistakes.