
Research article
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Medical students face a number of different stressors. These stressors manifest in psychological as well as in physical complaints. Using the Giessen Subjective Complaints List (GBB-24) and a specially developed survey, physical complaints were assessed in 293 first- and second-year students (185 women, 108 men). Women consistently report higher scores on all four GBB-24 subscales (exhaustion, gastric complaints, musculoskeletal complaints and cardiovascular complaints). Also compared with the normsample, the students report more physical complaints on all GBB-24 scales. Women report higher investment in preparing for exams, while men dedicate more time to compensatory behaviour and social contacts. During increased strains in preparation for exams students do not report higher substance use, although women report higher use of medications in these time periods.
Systemic inflammatory processes induced by infectious diseases, sepsis or chronic inflammatory auto-immune diseases can affect mood, neuropsychological functions and behavior. Typically, those behavioral changes include symptoms such as psychomotor slowing, social withdrawal, anhedonia and depressed mood, and are collectively termed “sickness behavior”. It is believed that the increased release of pro- and anti-inflammatory cytokines and hormones are mediating these behavioral effects and that peripheral cytokines are involved in the pathophysiology of neuropsychiatric disorders such as depression and schizophrenia. In humans, the effects of an acute systemic inflammatory response on neuropsychological function can be experimentally analyzed by administering bacterial endotoxins. This review provides an overview of studies in humans investigating the effects of experimentally induced inflammation on cognitive and emotional parameters and corresponding neural activities within the CNS. In addition, possible signaling pathways are outlined, of how information from the peripheral immune system is transmitted to the CNS during peripheral inflammation.
Objectives: Based on the Magdeburger Alcohol Tolerance Test for adults (MATT), a respective questionnaire version for adolescents was developed (J-MATT). The goal was to help identify adolescents with respect to the extent of their alcohol tolerance in order to allow an earlier detection of problematic alcohol consumption.
Methods: TheMATT (version with 50 items) was supplemented by 30 items addressing alcohol tolerance and consumption in adolescents. The J-MATT was completed by 160 subjects (aged 12–26 years). Factor and item analyses were accomplished using these data. The results were compared with reference samples of the MATT [medical students (N=164); adults without (N=165) and with alcohol dependency (N=41)].
Results: 23 items remained following factor and item analyses. Three factors of the J-MATT (alcohol tolerance/functional tolerance, physical performance, environment / function of alcohol consumption) correlated with consumed amounts of alcohol. The age of first consumption of alcohol was 12;10 ±1;10 (years; months). The amount of alcohol needed to subjectively perceive an effect was 62 g. Adolescents had higher alcohol tolerance than medical students and adults without alcohol dependency. Only adults with alcohol dependency showed higher alcohol tolerance levels than adolescents.
Conclusion: Reported alcohol consumption and tolerance levels of adolescents were alarmingly high and exceeded the established limits for very risky alcohol consumption. However, some of these effects may be explained by adolescents’ tendency to exaggerate.
Objectives: Paruresis is still a widely neglected form of social phobia. Data concerning the prevalence rates as well as possible sociodemographic risk factors or correlates are still missing. Nationally representative data on point prevalence of paruresis are presented herein.
Methods: Following a random-route procedure, more than 2500 subjects in Germany were visited and asked to complete a questionnaire about paruresis based on DSM-IV as well as sociodemographic variables. Main outcome measures were the prevalence of paruresis in Germany. In additition, associations of paruresis with sociodemographic correlates were examined.
Results: The overall prevalence of paruresis is 2.6%. For women and individuals with lower education the prevalence rate is higher than for men and individuals with higher education.
Conclusion: The results of this representative study show a higher prevalence of paruresis in women than in men and an overall prevalence rate which – compared to other disorders with similar prevalence rates – calls for more intense future research efforts.
Objectives: The Santo Daime Church is a religious community originally founded in Brazil which has increasingly attracted followers in Europe and worldwide. An important element of the religious ceremonies is the ingestion of a psychoactive substance known as ayahuasca. Ayahuasca is a psychoactive or visionary-state-inducing concoction of plants, which contains, amongst other substances, dimethyltryptamine and MAO-inhibitors like harmaline.
Methods: Within the framework of a longitudinal research project (2003 – 2012) Ayahuasca-consumers have been interviewed in Holland. Conclusions were drawn from interviews of 21 participants, done in three of totally fourteen measure points, on the basis of content analyses.
Results: The most important motives for the use of ayahuasca are predominantly religious or spiritual. Users also showed the intention of medicinalpsychotherapeutical self-treatment. 20 of the 21 persons interviewed clearly demonstrated these motives. Further important motives were the desire for social interaction (n=16) and the search for new or extraordinary experiences (n=17) brought about by the use of a psychoactive substance. Hedonistic motives, an intention to improve performance or motives based on underlying pathologies or disorders were negligible.
Conclusion: Based on the interviews of the members of the Santo Daime Church it becomes obvious that the reasons for the use of this psychoactive are manifold and should not be limited to pathologies like addiction.
Through the chosen approach it was possible to analyze a target-oriented consumption of psychoactive substances and to get insight into the desired effects of drug consumption.
