This paper presents an examination of filter-down theory in relation to the location and technological sophistication of manufacturing establishments within the UK pharmaceutical industry. By means of data drawn from a survey of eighty-three pharmaceutical manufacturing companies, the paper considers the technological sophistication both of firms and of plants according to their location as defined by settlement size, degree of urbanization, and their broader centre-periphery regional setting. Given the overall location of the UK pharmaceutical industry, it is shown that there is no significant technological bias in favour of firms or plants located in larger settlements, in more urbanized areas, or within more centrally located regions. In part this result was associated with the decentralized location of manufacturing units controlled by large technologically advanced corporate organizations. The survey data also revealed that on an intracorporate basis there was no evidence that more distant plants, in relation to their main innovation or headquarters location, tended to be less technologically sophisticated.
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References
1.
ABPI, 1977Directory of Members and Associated Companies (Association of the British Pharmaceutical Industry, London)
2.
AlderF M, 1970“The relationship between the income and price elasticities of demand for United States exports”Review of Economics and Statistics52313–319
3.
AmberG SAmberP S, 1962Anatomy of Automation (Prentice-Hall, Englewood Cliffs, NJ)
4.
AngilleyA S, 1973“Returns to scale in research in the ethical pharmaceutical industry”Journal of Industrial Economics2281–93
5.
AnsoffH I, 1965Corporate Planning (Penguin Books, Harmondsworth, Middx)
6.
BSO, 1976Classified List of Business: MLH 272, Pharmaceutical Chemicals and Preparations Business Statistics Office (HMSO, London)
7.
BSO, 1981Business Monitor, Fourth Quarter 1980: PQ 272, Pharmaceutical Chemicals and Preparations Business Statistics Office (HMSO, London)
8.
BurnsA F, 1934Production Trends in the United States since 1870 (National Bureau of Economic Research, New York)
9.
BuswellR JLewisE W, 1970“The geographical distribution of industrial research activity in the United Kingdom”Regional Studies4297–306
10.
CameronG, 1977“Economic renewal in the inner city: Glasgow”Architects Journal165215–217
11.
ComanorW S, 1965“Research and technical change in the pharmaceutical industry”Review of Economics and Statistics47182–190
12.
ComanorW SSchererF M, 1969“Patent statistics as a measure of technical change”Journal of Political Economy77392–398
13.
CoxN J, 1978“The analysis of categorical data”Area10355–358
14.
CrumR EGudginG, 1977‘Non-production activities in UK manufacturing industry’Regional Policy Series 3Collection Studies, Commission of the European Communities, Brussels
15.
DeanJ, 1950“Pricing policies for new products”Harvard Business Review2845–53
16.
EricksonR A, 1976“The filtering-down process: Industrial location in non-metropolitan areas”Professional Geographer28254–260
17.
EricksonR ALeinbachT R, 1979“Characteristics of branch plants attracted to non-metropolitan areas” in Nonmetropolitan Industrialisation Eds LonsdaleR ESeylerH L (Winston, Washington DC/John Wiley, New York) pp 57–78
EwersH-JWettmanR WBadeF-JKleineJKristH, 1979“Innovationsorientierte Regionalpolitik”Wissenschaftszentrum, Berlin
20.
FreemanC, 1963“The plastics industry: A comparative study of research and innovation”National Institute Economic Review2622–62
21.
GermidisD, 1977“Transfer of technology by multinational corporations and absorptive capacity of the developing countries: A synthesis” in Transfer of Technology by Multinational Corporations: Volume 1, A Synthesis and Country Case Study Ed. GermidisD (Development Centre of the Organisation for Economic Cooperation and Development, Paris) pp 10–43
22.
GoddardJ B, 1977“Urban Geography: City and Regional Systems”Progress in Human Geography1296–303
23.
GoddardJ BSmithI J, 1978“Changes in corporate control in the British urban system, 1972–1977”Environment and Planning A101073–1084
24.
GoodmanL AKruskalW H, 1954“Measures of association for cross classifications”Journal of the American Statistical Association49732–764
25.
GruberWMehtaDVernonR, 1967“The R and D factor in international investment of United States industries”Journal of Political Economy7520–37
26.
HallM, 1959“Introduction” in Made in New York Ed. HallM (Harvard University Press, Cambridge, MA) pp 1–18
27.
HastingsT, 1976“The characteristics of early adopters of new technology: An Australian study”Economic Record52239–259
28.
HelfgottR B, 1959“Women's and children's apparel” in Made in New York Ed. HallM (Harvard University Press, Cambridge, MA) pp 19–134
29.
HirschS, 1965“The United States electronics industry in international trade”National Institute Economic Review3492–97
30.
HirschS, 1967Location of Industry and International Competition (Clarendon Press, Oxford)
31.
HooverE MVernonR, 1959Anatomy of a Metropolis (Harvard University Press, Cambridge, MA)
32.
HundJ M, 1959“Electronics” in Made in New York Ed. HallM (Harvard University Press, Cambridge, MA) pp 241–325
33.
HunterLReidGBoddyD, 1970Labour Problems of Technological Change (George Allen and Unwin, London)
34.
IlberyB W, 1978“The analysis of categorical data: Reply”Area10358–359
35.
Jordan Dataquest, 1977The British Pharmaceuticals Industry (Jordan Dataquest, London)
36.
KeebleD E, 1968“Industrial decentralisation and the metropolis: The north west London case”Transactions of the Institute of British Geographers441–54
37.
KeebleD E, 1976Industrial Location and Planning in the United Kingdom (Methuen, London)
38.
KeebleD E, 1978a“Spatial policy in Britain: Comment 2”Area10123–125
39.
KeebleD E, 1978b“Spatial policy in Britain: Comment 4”Area10363–365
40.
KeebleD E, 1980“Industrial decline, regional policy and the urban-rural manufacturing shift in the United Kingdom”Environment and Planning A12945–962
41.
KennedyCThirlwallA P, 1972“Surveys in applied economics: Technical progress”Economic Journal8211–72
42.
KravisI B, 1956“Wages and foreign trade”Review of Economics and Statistics3814–30
43.
KrummeG, 1969“Notes on locational adjustment patterns in industrial geography”Geografiska Annaler51B15–19
44.
KuznetsS S, 1929“Retardation of industrial growth”Journal of Economic and Business History1534–560
45.
KuznetsS S, 1930Secular Movements in Production and Prices (Houghton Mifflin, Boston, MA)
46.
KuznetsS S, 1962“Inventive activity: Problems of definition and measurement” in The Rate and Direction of Inventive Activity Ed. NelsonR R (Princeton University Press, Princeton, NJ) pp 19–43
47.
LallS, 1979“The international allocation of research activity by US multinationals”Oxford Bulletin of Economics and Statistics41313–333
48.
LeverW, 1974“Manufacturing linkages and the search for supplies and markets” in Spatial Perspectives on Industrial Organisation and Decision-Making Ed. HamiltonF E I (John Wiley, Chichester, Sussex) pp 309–333
49.
LevittT, 1965“Exploit the product life cycle”Harvard Business Review4381–94
50.
LichtenburgR M, 1960One-tenth of a Nation (Harvard University Press, Cambridge, MA)
51.
McDermottP, 1977“Overseas investment and the industrial geography of the United Kingdom”Area9200–207
52.
McDermottP, 1979“Multinational manufacturing firms and regional developments: External control in the Scottish electronics industry”Scottish Journal of Political Economy26287–306
53.
MartinFSwanNBanksIBarkerGBeaudryR, 1979“The interregional diffusion of innovations in Canada”Minister of Supply and Services, Ottawa, Canada
54.
MasseyD BMeeganR A, 1978“Industrial restructuring versus the cities”Urban Studies15273–288
55.
NEDO, 1972Focus on Pharmaceuticals Chemicals Economic Development Committee, National Economic Development Office (HMSO, London)
56.
NorcliffeG B, 1975“A theory of manufacturing places” in Locational Dynamics of Manufacturing Activity Eds CollinsLWalkerD F (John Wiley, Chichester, Sussex) pp 19–59
57.
NortonR DReesJ, 1979“The product cycle and the spatial decentralization of American manufacturing”Regional Studies13141–151
58.
OakeyR P, 1979“An analysis of the spatial distribution of significant British industrial innovations” DP-25, Centre for Urban and Regional Studies, University of Newcastle upon Tyne, Newcastle upon Tyne, England
59.
OakeyR PThwaitesA TNashP A, 1980“The regional distribution of innovative manufacturing establishments in Britain”Regional Studies14235–253
60.
ParkerJ E S, 1974The Economics of Innovation: The National and Multinational Enterprise in Technological Change (Longman, Harlow, Essex)
61.
ParsonsG F, 1972“The giant manufacturing corporations and balanced regional growth in Britain”Area499–103
62.
PattonA, 1959“Top management's stake in the product life cycle”Management Review489–79
63.
PosnerM V, 1961“International trade and technical change”Oxford Economic Papers13323–341
64.
RakeD J, 1975“Spatial changes in industrial activity in the East Midlands since 1945: III, the footwear industry”The East Midland Geographer6173–184
65.
ReekieW D, 1973“Patent data as a guide to industrial activity”Research Policy2246–264
66.
ReekieW D, 1975The Economics of the Pharmaceutical Industry (Macmillan, London)
67.
ReekieW DWeberM H, 1979Profits, Politics and Drugs (Macmillan, London)
68.
ReesJ, 1979“Technological change and regional shifts in American manufacturing”Professional Geographer3145–54
69.
RobertsonT S, 1971Innovative Behaviour and Communication (Holt, Rinehart and Winston, New York)
70.
Sainsbury Report, 1967Report of the Committee into the Relationship of the Pharmaceutical Industry with the National Health Service Cmnd 3140 (HMSO, London)
71.
SalterW E G, 1966Productivity and Technical Changesecond edition (Cambridge University Press, Cambridge, England
72.
SandersB S, 1962“Some difficulties in measuring inventive activity” in The Rate and Direction of Inventive Activity Ed. NelsonR R (Princeton University Press, Princeton, NJ) pp 53–77
73.
SchumpeterJ A, 1939Business Cycles: A Theoretical, Historical and Statistical Analysis of the Capitalist Process (McGraw-Hill, New York)
74.
SchwartzmanD, 1976Innovation in the Pharmaceutical Industry (Johns Hopkins University Press, Baltimore, MD)
75.
SimonH A, 1965The Shape of Automation for Men and Management (Harper and Row, New York)
76.
St SlatterS P, 1977Competition and Marketing Strategies in the Pharmaceutical Industry (Croom Helm, London)
77.
SmithB M D, 1975“Employment in the inner city areas” WP-34, Centre for Urban and Regional Studies, University of Birmingham, Birmingham, England
78.
SolowR, 1960“Investment and technical change” in Mathematical Models in the Social Sciences Eds ArrowK JKarlinSSuppesP (Stanford University Press, Stanford, CA) pp 89–104
79.
StobaughR P, 1971“The neotechnology account of international trade: The case of petrochemicals”Journal of International Business Studies241–60
80.
TaylorM, 1978“Linkage change and organizational growth: The case of the West Midlands iron foundry industry”Economic Geography54314–336
81.
ThompsonW R, 1965A Preface to Urban Economics (Johns Hopkins University Press, Baltimore, MD)
82.
ThompsonW R, 1972“The national system of cities as an object of public policy”Urban Studies999–116
83.
ThorngrenB, 1970“How do contact systems affect regional development?”Environment and Planning409–427
84.
VernonJGusenP, 1974“Technical change and firm size: The pharmaceutical industry”Review of Economics and Statistics56294–302
85.
VernonM, 1971“Concentration, promotion and market share stability in the pharmaceutical industry”Journal of Industrial Economics19246–266
86.
VernonR, 1960Metropolis 1985 (Harvard University Press, Cambridge, MA)
87.
VernonR, 1966“International investment and international trade in the product cycle”Quarterly Journal of Economics80190–207
88.
VernonR, 1979“The product cycle hypothesis in a new international environment”Oxford Bulletin of Economics and Statistics41255–267
89.
WardellW MLasagnaL, 1975Regulation and Drug DevelopmentAmerican Enterprise Institute for Public Policy Research, Washington, DC
90.
WattsH, 1979“Large firms, multinationals and regional development: Some new evidence from the United Kingdom”Environment and Planning A1171–81
91.
WellsL, 1968“A product life-cycle for international trade?”Journal of Marketing321–6
92.
WellsS, 1969“Test of a product cycle model of international trade: US exports of consumer durables”Quarterly Journal of Economics83152–162
93.
WestawayJ, 1974“The spatial hierarchy of business, organisations and its implications for the British urban system”Regional Studies8145–155
94.
WoodP A, 1976Industrial Britain: The West Midlands (David and Charles, Newton Abbot, Devon)
95.
WoodwardJ, 1958Industry Organization: Theory and Practice (Oxford University Press, Oxford)
