Extramedullary hematopoiesis is a rare condition characterized by the formation of blood cells outside the bone marrow. It is commonly seen in patients with hematopoietic disorders or chronic anemia. Here, we report the case of a 55-year-old patient who had extramedullary hematopoiesis that manifested as an asymptomatic posterior mediastinal mass. Chest computed tomography showed a 30 × 35-mm mass located on the left side of the D11 vertebra. Laboratory investigations revealed no signs of anemia. The tumor was safely and completely removed using video-assisted thoracoscopic surgery. Pathological studies confirmed the extramedullary hematopoiesis nature of the tumor.
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