Abstract
Multiple biliary hamartomas (von Meyenberg complexes) are an uncommon benign biliary neoplasm detected incidentally on imaging. To our knowledge the appearances of multiple biliary hamartomas on microbubble contrast-enhanced ultrasound have not been previously described. We report a case using Coherent Contrast Imaging® and Agent Detection Imaging® techniques with the contrast agents Sonovue®and Levovist®. While both methodologies failed to differentiate these focal liver lesions from malignant neoplasms, they enhanced the conspicuity of the hamartomas. Radiologically-guided biopsy and histological analysis remain the reference standard in the diagnosis of multiple biliary hamartomas.