OBJECTIVE: To analyze intima-media thickness (IMT) of carotid artery and lipoprotein-associated phospholipase A2 (Lp-PLA2) in patients with coronary heart diseases of different types.
METHODS: A total of 1000 patients with suspicious coronary heart diseases were selected for carotid ultrasonography, coronary CT and Lp-PLA2, and divided into normal group, coronary atherosclerosis group and coronary heart disease group.
RESULTS: Statistical significance was observed in differences of IMT and Lp-PLA2 between normal group, coronary atherosclerosis group and coronary heart disease group. IMT and Lp-PLA2 were positively correlated. The worse the coronary heart disease, the higher the IMT or Lp-PLA2 values.
CONCLUSION: IMT and Lp-PLA2 ware closely correlated with coronary artery stenosis. IMT and Lp-PLA2 have certain predicting values for severity of coronary heart diseases. The combination of the two can improve noninvasive diagnosis of coronary heart diseases.
