Abstract

Dear Editor:
Facebook is being used as an innovative and cost-effective strategy for research recruitment.1,2 This novel approach is promising for researchers experiencing recruitment difficulties because of few eligible participants. Studies involving children with advanced cancer may require multiple data collection sites to achieve adequate sample sizes. Unfortunately, multisite studies pose additional challenges, such as high costs, large number of staff, and numerous institutional review boards. Facebook has been used to successfully recruit parents of children with cancer, 3 yet recruitment of more challenging groups such as children with relapsed or refractory cancer and their parents remains unexplored. This study examined the use of Facebook advertising to recruit children with advanced cancer and their parents.
Methods
Facebook advertisements were used to recruit children 7–17 years of age with relapsed or refractory cancer and their parent caregivers to participate in a digital storytelling project. We developed the advertisement (see Fig. 1) according to size, word count, and policies specified by Facebook. To reach parents, the advertisements targeted individuals of ages 18 years and above in the United States with interest terms related to childhood cancer. The ad contained a link to an electronic survey including eligibility questions. Eligible participants continued to complete demographic information and provide their contact information if willing to pilot the newly developed web-based digital storytelling intervention. Participants were eligible for a drawing to receive a $100 gift card.

Facebook advertisement example.
We determined a maximum total of $1810 for the campaign. Ad delivery was optimized for clicks to our website link, and Facebook automatically charged per impression. Facebook provided data on impressions (number of times advertisements are shown to users), clicks on the link, and dollars spent. We developed several advertising campaigns to fine-tune strategies (Table 1) to recruit 10 participants in a short time period (e.g., one month).
Results
Facebook delivered advertisements for 12 days (December 18, 2014—December 30, 2014). The ads generated 110,211 impressions, were shown to 86,156 people, and resulted in 839 survey website clicks. The campaign cost $536.92, averaging $0.64 per website click. Of 76 electronically screened individuals, 37 were eligible and 22 completed the survey. Among 14 eligible participants agreeing to personal contact, 7 enrolled in the digital story project and 7 refused.
Discussion
Compared with 10 eligible participants per year at our institution who met the same inclusion criteria, Facebook advertising was a feasible and effective strategy to quickly recruit a diverse sample of children with advanced cancer and their parents. Understanding the process involved in finding the best recruitment strategies is crucial. Researchers may benefit from piloting Facebook advertisements before launching larger studies. We revised our advertising campaign several times before having success. Similar advertisements and strategies used previously 3 were unsuccessful when first used in this study. Facebook advertising experts advised that algorithms had changed; strategies that worked previously may not work the same now or in the future. Useful resources for successful revisions included collaboration with marketing and Facebook advertising experts. Researchers developing Facebook advertising campaigns may consider these valuable resources during early phases.
This study was invaluable to launch a successful ad campaign for our larger RO1 currently in progress. Even so, we revised our RO1 advertising campaign again after three months, indicating the need for close monitoring of campaign responses that could indicate new or revised versions. We narrowed interest terms, which decreased the potential reach from >7 million to 4.6 million, to minimize ineligible people from receiving the ad. We recommend future pilot campaigns to last at least three months to allow time for such issues to arise and to be resolved before larger studies. More research is needed to examine Facebook recruitment methods specific to pediatrics.
Footnotes
Acknowledgments
Research reported in this publication was supported by the National Institute of Nursing Research of the National Institutes of Health under Award Number R01NR015353 and an American Cancer Society Institutional Research grant (IRG-58-009-54) to Dr. Terrah Foster Akard. Dr. Akard had full access to all of the data in the study and takes responsibility for the integrity of the data and the accuracy of the data analysis.
